Objective: The aim of this case report is to highlight harmful practice in treatment of fibroid with local herbs with consequent acquired gynaetresia. Method: This is a case report of a woman with uterine fibroid. The relevant information was obtained from her case file. Results: This is a case of a woman who was diagnosed of having uterine fibroid and was to have surgical management. She initially opted for treatment with local herbs and suffered acquired gynaetresia as a result of vaginal application of the herbs. She also had respiratory distress consequent to giant size of the tumor as a result of undue delay in receiving appropriate treatment. She eventually had abdominal total hysterectomy and bilateral salpingo-oophorectomy. Conclusion: Harmful practices in the treatment of uterine fibroid could result in disastrous consequences. Therefore, community enlightenment as regards appropriate treatment of fibroid should be undertaken to curtail the unwarranted consequences of harmful treatment.